The Wrong Blood Thinner

Warfarin had been the standard for APS for decades. Then DOACs hit the market — convenient, no blood draws, no dietary restrictions. But for patients with Antiphospholipid Syndrome, convenience came at a cost. This episode breaks down the pharmacology of warfarin versus DOACs, explains what the TRAPS trial would eventually prove, walks through the patient's prolonged hospitalization and devastating clinical decline, and introduces the legal concepts — proximate cause and preponderance of evidence — that will frame everything that follows.


On the Record is a deep-dive series from The Charted Defense that takes a real medical malpractice case apart — from the patient's first presentation through the courtroom. Each season follows one case across multiple episodes, walking through the medical records, the clinical decision-making, the legal filings, and the expert testimony on both sides. The goal isn't to pick winners — it's to find the moments where something could have gone differently and turn them into lessons for the next shift.